Researchers with relevant expertise contributing to HI³ Themes and Capacities. Not comprehensive of efforts throughout the Hub. Individuals marked with "*" also contribute to Cross-Cutting Capacities.
- Theme A — Interventions
- Theme B — Process Innovations
- Theme C — Health Intelligence
- Cross-Cutting Capacities
Theme A — Interventions
| Theme member | Institutes | Expertise |
|---|---|---|
| Allison McGeer* (Theme Lead) | Sinai Health | Clinical effectiveness, surveillance for infectious diseases, population and public health |
| Jennifer Gommerman* | UofT | Immunology, mucosal immunity, vaccines |
| Scott Gray-Owen* | UofT | Bacteriology, CL3 animal models, vaccines |
| Alan Bernstein* | UofT | Cell biology, vaccines, pathogen biology |
| Shayan Sharif* Leonardo Susta* | Guelph | Zoonotic pathogens, avian immune system |
| Sarah Wootton* | Guelph | Virology, egg-based vaccine production, pre-clinical models |
| Eric J. Arts* Stephen Barr Shawn Li Ryan Troyer Greg Dekaban Chil-Yong Kang Miguel Quiñones-Mateu | Western | HIV vaccines, vaccine seed banks, retroviral therapy, molecular virology, immunotherapies |
| Kun Ping Lu* Xiao Zhen Zhou | Western | NextGen biotherapeutics and biodiagnostics harnessing our body’s ability to fight disease |
| Samira Mubareka* | Sunnybrook | Zoonotic pathogens, one health |
| Robert Kozak* | Sunnybrook | Clinical microbiology, vaccines, emerging pathogens |
| Anne-Claude Gingras* Jeff Wrana* | Sinai Health | Proteomics, cell signaling, virus-host interactions, sequencing, automation |
| Tania Watts* Alberto Martin | UofT | Immunoprofiling of humans, mouse models |
| Pam Ohashi* | UHN | Immunoprofiling, T-cell development, cancer vaccines |
| Rupert Kaul* Mario Ostrowski* | UHN Unity Health | Mucosal Immunity, HIV, Clinical trials in diverse cohorts, vaccines, studies in Africa, immunoprofiling |
| Jun Liu* | UofT | Tuberculosis, intranasal vaccine delivery |
| Tak Mak* | UHN | Advanced preclinical models. |
| Charles Graham Stephen Archer Che Colpitts | Queen’s | Immunity, immune checkpoints Virus-host interactions, anti-viral strategies Molecular virology, anti-viral strategies |
| Aled Edwards Cheryl Arrowsmith | UofT | Drug discovery, structural genomics |
| Walid Houry* Justin Nodwell William Navarre Leah Cowen James Scott* | UofT | Broad-acting antimicrobial, antiviral and antifungal therapeutics |
| Alan Davidson Karen Maxwell | UofT | Innovative approaches to tackle antibiotic resistance using phage-based approaches |
| Costin Antonescu* Raffi Karshafian Stefania Impellizzeri Sarah Sabatinos | TMU | Identifying new antiviral drugs for the treatment of coronavirus disease and drug repurposing |
| Trevor Moraes | UofT | Biochemistry, drug discovery |
| Dustin Little | TMU | Host-pathogen interactions, bacteriology, glycobiology |
| Joseph McPhee | TMU | Bacterial regulatory systems, omptin proteases, enteropathogen virulence |
| Russell Viirre | TMU | Medicinal chemistry, molecular probes, therapeutics development |
| Michael Sefton* | UofT | Tissue engineering, drug delivery, precision medicine |
| Scott Prosser | UTM | Protein biochemistry, drug discovery |
| Roman Melnyk | SickKids | Bacterial virulence factors, novel therapeutics |
| John Parkinson | SickKids | Pathogen:microbiome interactions, computational biology, global health, parasitology |
Theme B — Process Innovations
| Theme member | Institutes | Expertise |
|---|---|---|
| Warren Chan* (Theme Lead) | UofT | Barcoding diagnostics, bioprocessing |
| Bowen Li Omar Khan | UofT | mRNA vaccine technologies, combinatorial delivery systems, lipid nanoparticles |
| Gang Zheng | UHN | Inorganic nanosystems |
| Aaron Wheeler Keith Pardee | UofT | Digital microfluidic diagnostics |
| Lisa Strug* | SickKids | Data sciences |
| Kamran Khan* | Unity Health | Data sciences, AI |
| Muhammad Mamdani | UofT | AI |
| Kenneth Ng Yufeng Tong | Windsor | Biochemical reagent specialists |
| Geoffrey Hinton* | UofT | Machine learning and AI |
| James Rini | UofT | Biochemical reagent specialist |
| Trevor Charles | Waterloo | Wastewater surveillance, microbiology |
| Marc Aucoin Hector Budman | Waterloo | Model-driven optimization of biomanufacturing processes |
| Radhakrishnan Mahadevan* | UofT | Metabolic Systems Engineering |
| Roderick Slavcev* | Waterloo | Bacteriophage engineering, vaccine development |
| Anita Layton | Waterloo | Computational modeling |
| Andrew Doxey | Waterloo | Computation biology |
| Sergey Krylov* | York | Analytical characterization and measurements |
| Shirley Tang* | Waterloo | Manufacturing, devices, sensors |
| Leo Chou | UofT | Nanomedicine, vaccines |
| Arezoo Emadi | Windsor | Novel biosensors, microbial diagnostics |
| Maxwell Smith | Western | Public health and infectious disease ethics, bioethics, health policy |
| Scott Tsai* | TMU | Nanobubbles, lab-on-chip |
| Lauren Cipriano | Western | Health economics, pharmacoeconomics, biotechnology, health policy evaluation |
| Gary Bader* | UofT | Computational biology, genomic technologies |
Theme C — Health Intelligence
| Theme member | Institutes | Expertise |
|---|---|---|
| Shelly Bolotin* (Theme Lead) | UofT | Public health, vaccinology, serosurveillance |
| Nelson Lee* | UofT | Public health and clinical interventions |
| Shaza Fadel | UofT | Public health, global health, immunology |
| David Fisman* | UofT | Public health and mathematical modelling |
| Jennifer Gibson | UofT | Public health and bioethics |
| Adalsteinn Brown* Geoffrey Anderson Sara Allin | UofT | Health services research |
| Kevin Brown Sarah Buchan | PHO | Public health epidemiology, vaccine effectiveness, transmission patterns |
| Kevin Schwartz Jeff Kwong* | PHO | Public health epidemiology, vaccine effectiveness, clinician |
| Phillip Awadalla* John McLaughlin | UofT | Public health, cohort studies |
| Jonathon Maguire* | Unity Health | Clinical medicine, pediatric cohort studies and clinical trials |
| Fahad Razak | Unity Health | Epidemiology, public health intelligence, clinical sciences, data sciences |
| Sharon Straus* | Unity Health | Public health intelligence, geriatrics; clinical trials and cohort studies (elders, aging) |
| Darrell Tan* | Unity Health | Public health intelligence, clinical trials and cohort studies in context of sexual health (LGBTQ2+) |
| Padmaja Subbarao Catherine Birken Upton Allen* | SickKids | Clinical medicine and applied research |
| Barry Pakes | UofT | Public health interventions, clinical medicine |
| Brian Schwartz | PHO | Public health and emergency preparedness |
| Kendall Soucie | Windsor | Socioeconomic determinants of health |
| Lisa Porter* | Windsor | Knowledge translation and emergency preparedness |
| Tara Moriarty* | UofT | Infectious disease, knowledge translation, science communication |
| Sharmistha Mishra* | Unity Health | Global health, mathematical modelling, socioeconomic determinants of transmission dynamics |
| Michelle Hladunewich | Sunnybrook | Clinical medicine and applied research, infectious diseases in patients with kidney disease |
| David Maslove* | Queen’s | Clinical medicine and applied research, global health, machine learning |
| Atul Humar Deepali Kumar | UHN | Clinical medicine, clinical trials and cohort studies on infectious diseases affecting immunosuppressed (transplant) patients; Transplant Infectious Diseases |
| Prabhat Jha* | Unity Health | Global health and population epidemiology, serosurveillance, vital statistics |
| Stephen Scherer* | SickKids | Host genomics |
| Erica di Ruggiero | UofT | Global health |
| Jianhong Wu Huaiping Zhu Jane Heffernan Seyed Moghadas | York | Mathematical disease modelling |
| Kelly Grindrod | Waterloo | Digital technologies for medication management, Vaccine hesitancy |
| Beate Sander* | UHN | Health Services, Mathematical Modeling, Public health, infectious disease modelling |
| Stephen Hwang* | Unity Health | Outbreak surveillance, cohort studies, in the context of homelessness |
| Josephine Wong | TMU | Health equity, community-engaged research, community resilience during COVID-19, migrant health |
| Mandana Vahabi | TMU | Global health, migrant health, health equity |
| Trevor Hart | TMU | Health of gender and sexual minorities, sexual health, community-based research and interventions |
| Samir Sinha | TMU | Policy and clinical interventions for aging populations; testing and vaccine rollout for aging populations (e.g. in LTCs) during COVID-19 |
| David Naylor* | UofT | Health systems, population health |
| Johnathan Gubbay* | PHO | Pathogen diagnostics and sequencing/genomics |
| Allison Sekuler | UofT | Aging populations, neurobiology |
Cross-Cutting Capacities
| Theme member | Institutes | Expertise |
|---|---|---|
| Prameet Sheth | Queen’s | Pathogen diagnostics and sequencing/genomics |
| Angela M. Cheung | UHN | Integrative medicine, genetic and clinical risk factors, function outcomes, quality of life, and health services research |
| Art Poon Michael Hallet R. Michael McKay | Western Western Windsor | Pathogen diagnostics and sequencing/genomics |
| Tony Mazzulli Vanessa Allen Susan Poutanen | Sinai Health | Clinical microbiology, pathogen surveillance, sequencing/genomics |
| Claire Jardine Dorothee Bienzle Scott Weese | Guelph | Zoonoses, ecology of disease, One Health, Animal Health Laboratory |
| Jennifer Guthrie | Western | Pathogen genomics and bioinformatics |
| Andrew Winterborn* Badru Moloo* | Queen’s UHN | Non-human primate modeling |
| Lori Frappier | UofT | Proteomics and viral virulence factors |
| Brian Raught | UHN | Proteomic platforms and cellular interactions |
| John Brumell | SickKids | Host-pathogen interactions |
| Mikko Taipale | UofT | Proteomics and systems biology |
| Jared Simpson | UofT | Genomics, sequencing technologies, computational biology |
| Alán Aspuru-Guzik | UofT | Machine learning, quantum computing, and automated chemistry |
| Jason Moffat | SickKids | Genetic networks and systems biology |
| Frederick Roth | UofT | Protein networks and computational biology |
| Doug Fraser | Western | Neurology and immunology |
| Dana Philpott | UofT | Host-pathogen interactions and microbiome |
| Robert J Botelho | TMU | Cell biology and immune function |
| Richard Gibson | Western | High containment facilities and antiretroviral resistance |
| Haibo Zhang | Unity Health | Respiratory viruses, lung organoid and animal models |
| David Brooks | UHN | Multi-pathogen co-infection, animal models, chronic viruses |
| John Dick | UHN | Immune system development, animal models |
| Sharon Walmsley | UHN | Clinical trials and HIV clinical management |
| Ewan Goligher | UHN | Clinical interventions and trials |
| Janet Dancey | Queen’s | Clinical trials |
| Isaac Bogoch | UHN | Tropical diseases and clinical epidemiology |
| Ashleigh Tuite | UofT | Epidemiological modelling |
| Kumar Murty | UofT | Mathematical modelling, data sciences |
| Rahul G. Krishnan | UofT | Machine learning and healthcare |
| Pooya Zadeh | Windsor | Machine learning and healthcare |
| Anna Goldenberg | SickKids | Machine learning and human disease |
| Amber Simpson | Queen’s | Machine learning and health informatics |
| Michael Brudno | UHN | Computational medicine |
| Jean-Philippe Julien | SickKids | Structural biology, vaccines and immunotherapeutics |
| Greg B. Gloor | Western | Computational Biology, Protein Evolution |
| Trevor Charles | Waterloo | Pathogen surveillance and sequencing |
| Subha Kalyaanamoorthy | Waterloo | Computational Biology and Chemistry |
| Rob Fowler | Sunnybrook | Clinical trials, clinical management, CIHR network of networks |
| Felix Ratjen | UHN | Clinical trials, pediatric medicine, clinical sciences |
| John Marshall | Unity Health | Clinical trials, immunopathology, CIHR network of networks |
| Theo Moraes | SickKids | Respirology, primary cell culture systems, viral pathobiology |
| Amy Wong | SickKids | Lung development, organoid systems |
| Liliana Attisano | UofT | Cell signalling, tissue development, organoid systems |
| Julien Muffat | SickKids | Neuroimmunology, virology, primary cell systems |
| Milica Radisic | UofT | Organ-on-a-chip engineering, cardiac modelling |
| Slava Epelman | UHN | Cardiology, viral infraction, pre-clinical modelling |
| Mark Servos | Waterloo | Wastewater surveillance, ecotoxicology |
| Lawrence Goodridge | Guelph | Wastewater surveillance, food microbiology |
| Amy Greer | Guelph | Disease modelling, Wastewater surveillance, |
| Jennifer Geddes-McAlister | Guelph | Host-pathogen interactions, proteomics |
| Stephen Brown | Queen’s | Wastewater monitoring, environmental analysis |
| Sarah Jane Payne | Queen’s | Wastewater monitoring, water engineering |
| Claire Oswald | TMU | Watershed hydrology, wastewater monitoring |
| Kim Gilbride | TMU | Wastewater monitoring, antibiotic resistance |
| Elizabeth Edwards | UofT | Wastewater monitoring, bioremediation |
| Hui Peng | UofT | Wastewater monitoring, environmental toxicology |
| Christopher DeGroot | Western | Wastewater monitoring, water decontamination processes |
| Bryan Coburn | UHN | Microbial genomics, pathobiology, clinical sciences |